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ABL1 — BCL10
Text-mined interactions from Literome
Horita et al., J Exp Med 2000
(Blast Crisis...) :
Here, we show that the interleukin 3-independent expression of the antiapoptotic protein,
Bcl-xL , is
induced by
Bcr-Abl through activation of signal transducer and activator of transcription ( Stat ) 5
Gesbert et al., Blood 2000
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
Bcr/Abl activates transcription of the
Bcl-X gene through STAT5
Chen et al., Oncogene 1997
:
Here we demonstrate that
v-Abl PTK activation is
followed by an approximately twofold increase in mRNA level of
Bcl-XL by 6 h and a corresponding increase in Bcl-XL protein level by 24 h. Bcl-xL RNA and protein decreased in IL-3 deprived cells in the absence of v-Abl PTK activity