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FOS — ZGLP1
Text-mined interactions from Literome
Tang-Christensen et al., Int J Obes Relat Metab Disord 2001
:
GLP-1 given centrally to naive rats
results in a marked induction of
c-Fos protein in the supraoptic nucleus, paraventricular nucleus of the hypothalamus ( PVN ) and central nucleus of the amygdala, but only a moderate increase in the arcuate nucleus
Yamamoto et al., J Neurosci 2003
:
GLP-1Rs are densely expressed in the AP, and peripheral GLP-1R agonists
induce Fos-IR in AP neurons to a greater degree than intracerebroventricular administration
Asarian et al., Am J Physiol Regul Integr Comp Physiol 2009
:
GLP-1 , on the other hand,
increased c-Fos expression similarly in the NTS of both genotypes and increased c-Fos expression more in the PVN and Arc of 2CR KO mice, but not WT mice
Zhang et al., Am J Physiol Regul Integr Comp Physiol 2012
:
Intravenous
GLP-1 induced comparable increases of hindbrain
c-Fos immunoreactivity in intact, capsaicin treated, and vagotomized rats
Thiele et al., Brain Res 1998
(Insulinoma) :
While central infusion of des His1 Glu9 exendin-4 also blocked
GLP-1 induced ( 10.0 microgram ) anorexia and
c-Fos expression, the antagonist produced no independent effects on food intake or c-Fos expression