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CSF2 — HLA-DRB1
Text-mined interactions from Literome
Celestin et al., J Immunol 2001
:
IL-5 and
GM-CSF induce
MHC class II and B7 expression on eosinophils and have been reported in some studies to induce eosinophils to present Ag to T cells
Iking-Konert et al., Clin Exp Immunol 2002
(Acute Disease...) :
Indeed, parallel studies with PMN of healthy donors showed that while IFN-gamma and granulocyte/macrophage
colony stimulating factor ( GM-CSF ) induced both,
MHC class II and CD83, tumour necrosis factor (TNF)-alpha selectively
induced de novo synthesis of CD83
Summerfield et al., Immunology 2003
:
Granulocyte-macrophage
colony stimulating factor and interleukin-3 were survival factors for this DC subset, and culture
induced an up-regulation of
MHC class II and CD80/86
Sebastián et al., J Immunol 2008
:
GM-CSF dependent expression of
MHC class II molecules was inhibited because CIITA was not induced
Willman et al., J Exp Med 1989
:
Regulation of
MHC class II gene expression in macrophages by hematopoietic
colony stimulating factors (CSF)
Gessl et al., Immunobiology 1995
:
The
induction of
MHC class II Ag synthesis by
GM-CSF on rat BMDM phi was confirmed at the mRNA level by Northern blot analysis employing cDNA probes encoding the RT1.B alpha
Imamura et al., J Neuroimmunol 1994
:
In contrast, granulocyte-macrophage
colony stimulating factor ( GM-CSF ) did not
affect the expression of
MHC class II antigen on naive cells and down-regulated IFN-gamma mediated induction of MHC class II antigen expression on microglia
Hawrylowicz et al., Immunology 1994
:
Granulocyte-macrophage
colony stimulating factor ( GM-CSF ) and interleukin-3 (IL-3) are weak
inducers of major histocompatibility complex (
MHC) class II expression on purified human blood monocytes ... We demonstrate that the capacity of dexamethasone to up-regulate
GM-CSF induced
MHC class II expression correlates with the capacity to up-regulate GM-CSF receptor, but not the interferon-gamma (IFN-gamma) receptor, in a highly dose dependent manner on monocytes ... These experiments suggest that dexamethasone may act to up-regulate
GM-CSF induced
MHC class II antigen expression on monocytes by up-regulating cytokine receptor expression
Gosselin et al., J Immunol 1993
:
Induction of
MHC class II on human polymorphonuclear neutrophils by granulocyte/macrophage
colony stimulating factor , IFN-gamma, and IL-3
Holt et al., Immunology 1997
:
Associated
GM-CSF induced up-regulation of major histocompatability complex (
MHC) class II and CTLA4 ligand expression by DC were also unaffected by dexamethasone phosphate ( DX ), reinforcing the view that the inhibitory effects of steroids on the T-cell activating functions of DC are restricted to steps upstream from presentation of processed antigen to the T-cell receptor ( TCR )