Gene interactions and pathways from curated databases and text-mining

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CSF2 — HLA-DRB1

Text-mined interactions from Literome

Celestin et al., J Immunol 2001 : IL-5 and GM-CSF induce MHC class II and B7 expression on eosinophils and have been reported in some studies to induce eosinophils to present Ag to T cells
Iking-Konert et al., Clin Exp Immunol 2002 (Acute Disease...) : Indeed, parallel studies with PMN of healthy donors showed that while IFN-gamma and granulocyte/macrophage colony stimulating factor ( GM-CSF ) induced both, MHC class II and CD83, tumour necrosis factor (TNF)-alpha selectively induced de novo synthesis of CD83
Summerfield et al., Immunology 2003 : Granulocyte-macrophage colony stimulating factor and interleukin-3 were survival factors for this DC subset, and culture induced an up-regulation of MHC class II and CD80/86
Sebastián et al., J Immunol 2008 : GM-CSF dependent expression of MHC class II molecules was inhibited because CIITA was not induced
Willman et al., J Exp Med 1989 : Regulation of MHC class II gene expression in macrophages by hematopoietic colony stimulating factors (CSF)
Gessl et al., Immunobiology 1995 : The induction of MHC class II Ag synthesis by GM-CSF on rat BMDM phi was confirmed at the mRNA level by Northern blot analysis employing cDNA probes encoding the RT1.B alpha
Imamura et al., J Neuroimmunol 1994 : In contrast, granulocyte-macrophage colony stimulating factor ( GM-CSF ) did not affect the expression of MHC class II antigen on naive cells and down-regulated IFN-gamma mediated induction of MHC class II antigen expression on microglia
Hawrylowicz et al., Immunology 1994 : Granulocyte-macrophage colony stimulating factor ( GM-CSF ) and interleukin-3 (IL-3) are weak inducers of major histocompatibility complex ( MHC) class II expression on purified human blood monocytes ... We demonstrate that the capacity of dexamethasone to up-regulate GM-CSF induced MHC class II expression correlates with the capacity to up-regulate GM-CSF receptor, but not the interferon-gamma (IFN-gamma) receptor, in a highly dose dependent manner on monocytes ... These experiments suggest that dexamethasone may act to up-regulate GM-CSF induced MHC class II antigen expression on monocytes by up-regulating cytokine receptor expression
Gosselin et al., J Immunol 1993 : Induction of MHC class II on human polymorphonuclear neutrophils by granulocyte/macrophage colony stimulating factor , IFN-gamma, and IL-3
Holt et al., Immunology 1997 : Associated GM-CSF induced up-regulation of major histocompatability complex ( MHC) class II and CTLA4 ligand expression by DC were also unaffected by dexamethasone phosphate ( DX ), reinforcing the view that the inhibitory effects of steroids on the T-cell activating functions of DC are restricted to steps upstream from presentation of processed antigen to the T-cell receptor ( TCR )