Eliasz et al., Oncogene 2010
(Adenocarcinoma...) :
Inhibition of Notch-1 caused reduced IGF-1R expression, whereas forced Notch-1 expression yielded opposite effects ... Chromatin immunoprecipitation experiments suggested Notch-1 direct regulation of the IGF-1R promoter
Medyouf et al., J Exp Med 2011
(Precursor T-Cell Lymphoblastic Leukemia-Lymphoma) :
Furthermore, IGF1R is a Notch1 target, and Notch1 signaling is required to maintain IGF1R expression at high levels in T-ALL cells