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HMOX1 — TP53

Text-mined interactions from Literome

Meiller et al., Nucleic Acids Res 2007 : We show that the expression of Haeme-oxygenase 1 (HO-1) , a stress-inducible gene that codes for an enzyme having antioxidant properties, is stimulated in a p53 dependent manner in the thymus and spleen of irradiated mice
Wang et al., Circulation 2010 (Chronic Disease...) : Moreover, myocyte-specific HO-1 overexpression in HF promoted tissue neovascularization and ameliorated myocardial p53 expression ( 2-fold reduction ) and apoptosis
Nam et al., Oncogene 2011 (Colorectal Neoplasms) : Consistently, p53 , but not its homologue p73, activated HO-1 expression and was bound to the HO-1 promoter specifically only upon H ( 2 ) O ( 2 ) treatment
Skrzypek et al., Antioxid Redox Signal 2013 (Carcinoma, Non-Small-Cell Lung...) : HMOX1 also up-regulated p53 , down-regulated angiopoietin-1 (Ang-1) and mucin-5AC (MUC5AC), reduced proliferation, migration, and diminished angiogenic potential