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IL6 — ZFP36
Text-mined interactions from Literome
Van Tubergen et al., Cancer 2011
(Carcinoma...) :
Tristetraprolin regulates
interleukin-6 , which is correlated with tumor progression in patients with head and neck squamous cell carcinoma ... Conversely, overexpression of
TTP in HNSCC cells
led to decreased secretion of
IL-6 , VEGF, and PGE ( 2 ) ... The results of the current study demonstrated that down-regulation of
TTP in HNSCC enhances mRNA stability and
promotes secretion of
IL-6 , VEGF, and PGE ( 2 )
Brahma et al., Obesity (Silver Spring) 2012
(Obesity) :
Zfp36 inhibited basal and lipopolysaccharide (LPS) stimulated
interleukin-6 (IL-6) expression in adipocytes
Qin et al., Nutrition 2012
(MAP Kinase Signaling System) :
Ex vivo, the CE significantly decreased the amount of apolipoprotein-B48 secretion into the media,
inhibited the mRNA expression of genes of the inflammatory cytokines,
interleukin-1ß , interleukin-6, and tumor necrosis factor-a, and induced the expression of the anti-inflammatory gene,
Zfp36
Hochdörfer et al., Cell Signal 2013
:
LPS induced production of TNF-a and
IL-6 in mast cells is dependent on p38 but
independent of
TTP