Gene interactions and pathways from curated databases and text-mining

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PKD1 — TNF

Text-mined interactions from Literome

Yamashita et al., Int Immunopharmacol 2010 : Pharmacological inhibition of PKD strongly inhibited production of interleukin (IL)-13 and tumor necrosis factor (TNF)-alpha induced by FcepsilonRI stimulation, and the overexpression of PKD significantly increased the IL-13 and TNF-alpha production
Rodriguez Perez et al., Am J Physiol Gastrointest Liver Physiol 2011 : TNF-a , while having no detectable effect on the activation of PKD when added alone, augmented PKD activation stimulated by LPA, as measured by PKD autophosphorylation at Ser ( 910 )