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CD79A — TGFB3
Text-mined interactions from Literome
Goodrich et al., Cytokine 1998
:
Depletion of the IEC-6 supernatant using cytokine specific antibodies revealed that both interleukin 6 (IL-6) and
transforming growth factor beta ( TGF-beta ) were
responsible for the enhanced
IgA secretion while TGF-beta suppressed IgM secretion
Lai et al., J Am Soc Nephrol 2003
(Glomerulonephritis, IGA) :
Polymeric
IgA1 from patients with IgA nephropathy
upregulates transforming growth factor-beta synthesis and signal transduction in human mesangial cells via the renin-angiotensin system
Ogawa et al., Early Hum Dev 2004
:
Role of
transforming growth factor-beta in breast milk for initiation of
IgA production in newborn infants
Coffman et al., Semin Immunol 1989
:
Recent evidence suggests that
transforming growth factor-beta induces switching to
IgA , despite the inhibitory activity on other isotypes
Hummelshoj et al., Scand J Immunol 2006
:
All analogues reduced anti-CD40 Ab +
transforming growth factor ( TGF ) -beta induced
IgA production compared with cultures stimulated with anti-CD40 Ab and TGF-beta alone
Massacand et al., PloS one 2008
:
The ability of PP-DC to promote anti-CD40 dependent
IgA was partially
dependent on retinoic acid ( RA ) and
transforming growth factor ( TGF ) -beta , whilst BAFF and APRIL signaling were not required
Smits et al., Mucosal Immunol 2009
(Disease Models, Animal...) :
CTB caused a
transforming growth factor-beta dependent rise in antigen-specific
IgA in the airway luminal secretions, which was necessary for its preventive and curative effect, as all effects of CTB were abrogated in mice lacking the luminal IgA transporting polymeric Ig receptor
Armitage et al., J Immunol 1993
:
Although
transforming growth factor-beta only partially
inhibited secretion of IgM, IgG1, and
IgA , it was strongly suppressive for IgG4 and IgE production