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CTLA4 — IL13

Text-mined interactions from Literome

Riley et al., J Immunol 2001 : In addition to inhibiting cellular proliferation, CTLA-4 engagement prevented ICOS costimulated T cells from producing IL-4, IL-10, and IL-13 ... Second, on preactivated cells that had high levels of ICOS expression, CTLA-4 ligation blocked the ICOS mediated induction of IL-4, IL-10, and IL-13 , suggesting an interference with downstream signaling pathways
Blazevic et al., J Clin Immunol 2001 : Inhibition studies using the B7-binding fusion protein CTLA4Ig and antibodies against CD80 and CD86 demonstrate that CTLA4Ig and anti-CD86 inhibited influenza-specific T cell proliferation, interleukin (IL)-2 and interferon (IFN)-gamma production, and generation of influenza-specific CD8+ CTL
Lordan et al., J Allergy Clin Immunol 2001 (Asthma) : In contrast, allergen enhanced production of IL-5 and IL-13 by PBMC cultures from the same subjects, and this was inhibited effectively by CTLA-4Ig