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EDN1 — NOX1
Text-mined interactions from Literome
Duerrschmidt et al., Biochem Biophys Res Commun 2000
:
Endothelin-1 induces
NAD ( P ) H oxidase in human endothelial cells
Wingler et al., Free Radic Biol Med 2001
:
Neither the vasoconstrictor
endothelin 1 ( up to 500 nM, 1-24 h ) nor lipopolysaccharide ( up to 100 ng/ml, 1-24 h )
had any effect on
Nox1 and Nox4 expression in these cells
Rask-Madsen et al., Arterioscler Thromb Vasc Biol 2005
(Arteriosclerosis...) :
Furthermore, the review summarizes studies that implicate PKC in promoting proatherogenic mechanisms or inhibiting antiatherogenic mechanisms, including studies of endothelial dysfunction ; gene induction and
activation of vascular
NAD ( P ) H oxidase ; endothelial nitric oxide synthase expression and function
; endothelin-1 expression ; growth, migration, and apoptosis of vascular smooth muscle cells ; induction of adhesion molecules ; and oxidized low-density lipoprotein uptake by monocyte derived macrophages ... Furthermore, the review summarizes studies that implicate PKC in promoting proatherogenic mechanisms or inhibiting antiatherogenic mechanisms, including studies of endothelial dysfunction ; gene induction and
activation of vascular
NAD ( P ) H oxidase ; endothelial nitric oxide synthase expression and function ;
endothelin-1 expression ; growth, migration, and apoptosis of vascular smooth muscle cells ; induction of adhesion molecules ; and oxidized low-density lipoprotein uptake by monocyte derived macrophages
Lund et al., Toxicological sciences : an official journal of the Society of Toxicology 2005
:
Endothelin-1 mediated
increase in reactive oxygen species and
NADPH Oxidase activity in hearts of aryl hydrocarbon receptor (AhR) null mice
Loomis et al., J Pharmacol Exp Ther 2005
:
Experiments were designed to test the hypothesis that elevated levels of
endothelin 1 (ET-1) in the vasculature
activate NADPH oxidase and/or uncoupled nitric-oxide synthase (NOS), resulting in O2-* production, and mediate increased constriction
Banes-Berceli et al., Vascul Pharmacol 2005
(Diabetes Mellitus, Experimental) :
Endothelin-1 activation of JAK2 in vascular smooth muscle cells
involves NAD ( P ) H oxidase derived reactive oxygen species
Laplante et al., Can J Physiol Pharmacol 2006
(Cardiovascular Diseases) :
In this review, we describe the
role of
endothelin-1 in
NAD ( P ) H oxidase signalling after a sustained stimulation by angiotensin II
Dong et al., Zhongguo Dang Dai Er Ke Za Zhi 2006
:
[
Effect of
NADPH oxidase on hypoxia-inducible factor-1alpha and
endothelin-1 expression in human umbilical endothelial cells and its possible mechanism ] ... To study the
effect of
NADPH oxidase on hypoxia-inducible factor (HIF)-1alpha and
endothelin (ET)-1 expression in human umbilical endothelia cells ( HUVECs ) and its possible mechanism
An et al., Cardiovasc Res 2007
:
NADPH oxidase mediates angiotensin II-induced
endothelin-1 expression in vascular adventitial fibroblasts
Cheng et al., Acta Pharmacol Sin 2009
(Hypertrophy) :
We hypothesized that dispersed
NADPH oxidase , protein kinase Cepsilon ( PKCepsilon ), early response gene (ERG), and matrix metalloproteinase 9(MMP-9) across the heart by isoproterenol ( ISO ) medication might be
mediated by the
endothelin ( ET ) - ROS pathway
Dammanahalli et al., J Hypertens 2011
:
In addition, IL-10KO increased
endothelin-1 levels in plasma and aortas, and this effect was partially
blocked by silencing of
Nox1
Liu et al., J Huazhong Univ Sci Technolog Med Sci 2013
:
Effect of
NADPH oxidase inhibitor apocynin on the expression of hypoxia induced factor-1a and
endothelin-1 in rat carotid body exposed to chronic intermittent hypoxia