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LEF1 — NOTCH1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: NOTCH1 — LEF1 (direct interaction, pull down) Ross et al., Mol Cell Biol 2001*
• IRef Hprd Interaction: LEF1 — NOTCH1 (in vitro) Ross et al., Mol Cell Biol 2001*
• IRef Hprd Interaction: LEF1 — NOTCH1 (in vivo) Ross et al., Mol Cell Biol 2001*
• IRef Ophid Interaction: LEF1 — NOTCH1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: LEF1 — NOTCH1 (aggregation, confirmational text mining) Ross et al., Mol Cell Biol 2001*

Text-mined interactions from Literome

Chao et al., Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2004 : An alternative, more direct, approach to expanding stem cells could be achieved by specific genetic pathways known or believed to support primitive HSC proliferation such as Notch-1 receptor activation, Wnt/LEF-1 pathway induction , telomerase or the Homeobox ( Hox ) gene products
Ishitani et al., Nat Cell Biol 2005 : Furthermore, activation of LEF1 does not affect Notch activity or vice versa ... These findings reveal that Nrarp independently regulates canonical Wnt and Notch signalling by modulating LEF1 and Notch protein turnover, respectively