◀ Back to NOTCH1

NOTCH1 — RUNX3

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: RUNX3 — NOTCH1 (physical association, affinity chromatography technology) Gao et al., Exp Cell Res 2010*
• IRef Biogrid Interaction: RUNX3 — NOTCH1 (direct interaction, pull down) Gao et al., Exp Cell Res 2010*
• IRef Biogrid Interaction: RUNX3 — NOTCH1 (colocalization, imaging technique) Gao et al., Exp Cell Res 2010*

Text-mined interactions from Literome

Van de Walle et al., Blood 2009 : High Notch activity increases DTX1, NRARP, and RUNX3 expression, genes that are down-regulated during alphabeta-lineage differentiation
Giambra et al., Nat Med 2012 (Precursor T-Cell Lymphoblastic Leukemia-Lymphoma) : We also show that PKC-? is regulated by a new pathway in which NOTCH1 induces runt related transcription factor 3 ( RUNX3 ), RUNX3 represses RUNX1 and RUNX1 induces PKC-?