Buechner et al., Differentiation 2011
(Neuroblastoma) :
Mir-21 was up-regulated during cell differentiation, but inhibition of mir-21 did not prevent this process
Terao et al., J Biol Chem 2011
(Breast Neoplasms) :
In ERa ( + ) cells, retinoid dependent induction of miR-21 is due to increased transcription of the MIR21 gene via ligand dependent activation of the nuclear retinoid receptor, RARa