Gene interactions and pathways from curated databases and text-mining

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ANG — ANXA6

Text-mined interactions from Literome

Li et al., Am J Physiol Lung Cell Mol Physiol 2002 : ANG IV significantly increased upstream phosphatidylinositide (PI) 3-kinase ( PI3K ), PI-dependent kinase-1 (PDK-1), extracellular signal related kinases ( ERK1/2 ), and protein kinase B-alpha/Akt (PKB-alpha) activities, as well as downstream p70 ribosomal S6 kinase (p70S6K) activities and/or phosphorylation of these proteins
Kanda et al., Cancer Res 2005 : p70 S6 kinase (p70 S6K) was activated by Ang1-treatment , although this activation was blocked by a PI3K inhibitor, LY294002
Moon et al., Int J Tissue React 2005 : Wortmannin and rapamycin, an inhibitor of mTOR, suppressed Ang1 induced p70 S6 kinase phosphorylation and partially inhibited the Ang1 induced anti-apoptotic effect