Gene interactions and pathways from curated databases and text-mining

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FGF16 — PDGFB

Text-mined interactions from Literome

Wondergem et al., Atherosclerosis 2004 : Compared to cultures exposed to injury alone, radiation induced significant ( P < 0.05 ) increases in mRNA levels of IL-8 ( 1.35 +/- 0.10-fold increase at 4h ), FGF-2 ( 1.62 +/- 0.10-fold at 4h ; 1.76 +/- 0.33-fold at 24h ) and IL-1beta ( 2.76 +/- 0.40-fold at 24h ), whereas mRNA levels of TGF-beta1, PDGF-A and PDGF-B increased about 1.2-fold
Yamamoto et al., J Biol Chem 2008 : PDGF-AA induced the expression of the fibroblast growth factor genes Fgf3 and -7, and PDGF-BB induced the expression of Fgf1, -3, -7, and -10, whereas short interfering RNA for Pdgfa and Pdgfb inhibited the expression of Fgf3, -7, and -10, indicating that PDGFs regulate Fgf gene expression in SMG mesenchyme