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EPHB2 — SOCS6

Text-mined interactions from Literome

Mooney et al., J Biol Chem 2001 (Insulin Resistance) : SOCS-1 and SOCS-6 do not inhibit insulin dependent IR autophosphorylation, but both proteins inhibit insulin dependent activation of ERK1/2 and protein kinase B in vivo and IR-directed phosphorylation of IRS-1 in vitro
Bayle et al., J Biol Chem 2004 : SOCS6 reduced SCF induced activation of ERK1/2 and p38 but not activation of AKT or STATs in Ba/F3, murine embryonic fibroblast (MEF), or COS-7 cells ... SOCS6 did not impair ERK and p38 activation by other stimuli
Hwang et al., Biochem Biophys Res Commun 2007 (MAP Kinase Signaling System) : We found that both Erk and Pkcdelta activation were required for the increased SOCS6 stability by PMA ... In addition, we demonstrated that PMA, insulin, and PDGF increased both the stability of endogenous expressed SOCS6 and Erk activation in MDA-MB231 cells
Vlacich et al., Islets 2010 (Hyperglycemia...) : Overexpression of SOCS6 inhibited glucose induced ERK1/2 activation, strongly suggesting that Pim3 regulates ERK1/2 activity through SOCS6