Gene interactions and pathways from curated databases and text-mining

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CSF2 — PARP1

Text-mined interactions from Literome

Tsukamoto et al., J Biol Chem 1999 : Retroviral overexpression of SPA-1 in promyelocytic 32D cells also inhibited both activation of Rap1 and induction of cell adhesion by granulocyte colony stimulating factor without affecting differentiation
Murata-Ohsawa et al., Int J Mol Med 2004 (MAP Kinase Signaling System) : GM-CSF stimulation induced the cleavage of PARP , which is the key molecule for differentiation and apoptosis ... We found that incubation with Delta-1 significantly suppressed the GM-CSF induced cleavage of PARP ... Taken together, we found that Notch activation induced by Delta-1 partially inhibited GM-CSF induced differentiation, growth suppression, and apoptosis, along with reducing the GM-CSF induced cleavage of PARP