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ATF4 — CREB3
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Schinelli et al., J Neurosci 2001
:
By using selective protein kinase inhibitors and expression of dominant negative Rap1 protein, we also found that the Rap1/PKC/ERK dependent pathway
induces the phosphorylation of
activating transcription factor-1 , CREB, and Elk-1, whereas the p38MAPK dependent pathway only causes
CREB phosphorylation
Kajimura et al., J Exp Med 2011
(Bone Resorption) :
We show that the sympathetic tone signals in the osteoblasts to inhibit
CREB ( cAMP-responsive element binding protein ) phosphorylation and thus decrease osteoblast proliferation and to
promote ATF4 phosphorylation and thus increase RANKL ( receptor activator of NF-?B ligand ) expression, which then stimulates osteoclast differentiation