Gene interactions and pathways from curated databases and text-mining

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CD44 — PSEN1

Text-mined interactions from Literome

Murakami et al., Oncogene 2003 (Central Nervous System Neoplasms...) : Furthermore, we showed that PS1 is redistributed to ruffling areas of the plasma membrane similarly to CD44 after TPA treatment, supporting our biochemical observation that PS1 is involved in the intramembranous cleavage of CD44
Cui et al., Blood 2006 : We report now that the intracellular domain of CD44 ( CD44ICD ) is cleaved in macrophages undergoing fusion and that presenilin inhibitors prevent the release of CD44ICD and fusion