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IRF6 — MIF

Text-mined interactions from Literome

Schmidt-Supprian et al., Eur Cytokine Netw 2000 (Inflammation) : Inhibition of MIF release by APC was found to be independent of TNF, as stimulation of MIF release by LPS was unaltered in the presence of anti-TNF antibodies
Otsubo et al., Biol Pharm Bull 2002 : Whether the suppression of tumor necrosis factor-alpha (TNF-a), interleukin (IL)-8, IL-6, IL-1beta, and macrophage migration inhibitory factor ( MIF ) was reduced by lipopolysaccharide (LPS) in monocytes was examined
Khan et al., Hum Immunol 2002 (Shock, Septic) : This counteracting effect of NMPF paralleled the downregulation of the effects of LPS on the production of macrophage migration inhibitory factor ( MIF ) by spleen cells, on the plasma level of liver aminotransferase, and on the expression of several splenic lymphocyte and macrophage surface markers
Iwaki et al., Lab Invest 2003 (Disease Models, Animal...) : mMIF level in the liver of mice infected with AxCA-mMIFAS showed a significant reduction in MIF production in response to BCG-LPS compared with mice treated without viral infection and with AxCA-mMIFS
Maxime et al., J Infect Dis 2005 (Shock, Septic) : In culture, spontaneous release of MIF and release induced by lipopolysaccharide (LPS) , heat killed staphylococci, and red blood cell lysates were significantly higher in patients than in control subjects ... PBMCs from patients treated with glucocorticoids showed a lower release of MIF in response to LPS , heat killed Escherichia coli, and peptidoglycan than did PBMCs from untreated patients and showed levels similar to PBMCs from healthy control subjects
D'Souza El-Guindy et al., Alcohol 2007 (Alcoholic Intoxication...) : The LPS induced expression of IL-1beta, IL-6, MIF , gp130, and receptors IL-1RI, IL-1RII, and IL-6Ralpha were also significantly impaired by EtOH
Damico et al., Am J Respir Cell Mol Biol 2008 : We show here that silencing MIF expression by RNA interference ( MIF siRNA ) dramatically reduces MIF mRNA expression and the LPS induced increase in MIF protein levels, thereby sensitizing HPAECs to LPS induced cell death
Lehmann et al., Biofactors 2008 (Sepsis) : However, in survivors LPS ex vivo stimulation increased MIF secretion but not in non-survivors of sepsis ( p < 0.05 )
Han et al., Journal of the Korean Surgical Society 2012 : The effect of HTS on LPS induced MIF was evaluated in monocyte with 1 µg/mL LPS
Zheng et al., World J Gastroenterol 2012 (Lymphatic Metastasis...) : LPS can significantly promote MKN-45 cell proliferation ( 3.027 ± 0.388 vs 4.201 ± 0.092, P < 0.05 ), induce MIF production ( 54.333 ± 2.906 pg/mL vs 29.667 ± 3.180 pg/mL, P < 0.01 ) and cell surface expression of CD74 ( 75.6 % ± 4.046 % vs 9.4 % ± 0.964 %, P < 0.01 ) at LPS concentration of 1 µg/mL compared to medium control
Li et al., J Periodontal Res 2013 (Chronic Periodontitis...) : The in vitro study analyzed the effects of P. gingivalis LPS on the expression of MIF in a reconstituted human gingival epithelia ( RHGE ) model
Nishihira et al., Biochem Mol Biol Int 1996 : The pathophysiological role of MIF in HL-60 cells has not been fully understood ; however, the regulation of MIF mRNA expression by LPS suggests the possibility that the cytokine plays an important role in inflammatory events of leukemia
Nishihira et al., Cytokine 1998 : The precise pathophysiological role of MIF in HUVEC has not been fully understood ; however, the upregulation of MIF mRNA expression in vascular endothelial cells by LPS stimulation suggests the possibility that the cytokine plays an important role in systemic inflammatory events such as endotoxaemia