Gene interactions and pathways from curated databases and text-mining

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EGF — REN

Text-mined interactions from Literome

Shibayama et al., Front Biosci (Elite Ed) 2013 : Role of ( pro ) renin receptor in Ang II-mediated EGF receptor transactivation ... These data indicate that the ( pro ) renin receptor mediates EGF receptor transactivation in both Ang II-dependent and -independent pathways
Antonipillai et al., Hypertension 1993 : Because EGF is localized in the kidney, we have studied the direct effects of EGF on renin secretion using both static incubations and perifusions of rat renal cortical slices ... EGF at 5 x 10 ( -9 ) M significantly inhibited renin secretion in static incubations ( control, 100 +/- 3 % ; EGF, 72 +/- 3 % ; p < 0.001 ) ... None of these agents altered EGF mediated renin inhibition