Gene interactions and pathways from curated databases and text-mining

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CD46 — IL31

Text-mined interactions from Literome

Marie et al., Nat Immunol 2002 (Dermatitis, Contact...) : We found that engagement of CD46-1 or CD46-2 differentially affected CD8 ( + ) T cell cytotoxicity, CD4 ( + ) T cell proliferation, interleukin 2 (IL-2) and IL-10 production as well as tyrosine phosphorylation of Vav in T lymphocytes
Yagi et al., Int J Mol Med 2007 : IL-31 dose-dependently induced secretion of IL-6, IL-8, GRO-alpha, MCP-3 , MMP-1 and MMP-3