UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

BioCarta induction of apoptosis through dr3 and dr4/5 death receptors: DR3/TRADD/FADD/TRAF2/RIP/Caspase 8/Caspase 10/APO-3L complex (TNFRSF25-TRADD-FADD-TRAF2-RIPK1-CASP8-CASP10-TNFSF12) → APO-3L (TNFSF12) (modification, collaborate)
BioCarta induction of apoptosis through dr3 and dr4/5 death receptors: DR3/TRADD/FADD/TRAF2/RIP/Caspase 8/Caspase 10/APO-3L complex (TNFRSF25-TRADD-FADD-TRAF2-RIPK1-CASP8-CASP10-TNFSF12) → DR3/TRADD/FADD/TRAF2/RIP/Caspase 8/Caspase 10 complex (TNFRSF25-TRADD-FADD-TRAF2-RIPK1-CASP8-CASP10) (modification, collaborate)
BioCarta induction of apoptosis through dr3 and dr4/5 death receptors: APO-3L (TNFSF12) → DR3/TRADD/FADD/TRAF2/RIP/Caspase 8/Caspase 10 complex (TNFRSF25-TRADD-FADD-TRAF2-RIPK1-CASP8-CASP10) (modification, collaborate)
BioCarta induction of apoptosis through dr3 and dr4/5 death receptors: DR3/TRADD/FADD/TRAF2/RIP/Caspase 8/Caspase 10/APO-3L complex (TNFRSF25-TRADD-FADD-TRAF2-RIPK1-CASP8-CASP10-TNFSF12) → Caspase 3 (CASP3) (modification, activates)
BioCarta induction of apoptosis through dr3 and dr4/5 death receptors: DR3/TRADD/FADD/TRAF2/RIP/Caspase 8/Caspase 10/APO-3L complex (TNFRSF25-TRADD-FADD-TRAF2-RIPK1-CASP8-CASP10-TNFSF12) → Caspase 3 (active) (CASP3) (modification, activates)
BioCarta induction of apoptosis through dr3 and dr4/5 death receptors: DR3/TRADD/FADD/TRAF2/RIP/Caspase 8/Caspase 10/APO-3L complex (TNFRSF25-TRADD-FADD-TRAF2-RIPK1-CASP8-CASP10-TNFSF12) → MAP3K14 (modification, activates)