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CD8A — SLC19A2
Text-mined interactions from Literome
Morelli et al., Transplantation 2000
(Acute Disease) :
Here, we compared the capacity of in vitro generated normal liver immature DC and FL-treated donor liver DC to induce alloimmune CD4+ T helper ( Th ) 1/Th2 and
CD8+ T cytotoxic (Tc) 1/Tc2 responses , in vitro and in vivo
Liu et al., J Gene Med 2003
(Neoplasms) :
a type 1 immune response comprising CD4 ( + ) Th1 and
CD8 ( + )
Tc1 activation and ( ii )
Li et al., Infect Immun 2004
(Disease Susceptibility...) :
IL-12 p40 levels in serum and magnitudes of CD4+ Th1 and
CD8+ Tc1 responses against Listeria antigen were significantly higher in AC-1 treated mice than in PBS treated mice
Pinchuk et al., J Immunol 2005
(Chlamydophila Infections) :
Recently we reported that Cpn infected mice generate an MHC class I-restricted
CD8 ( + )
Tc1 response against various Cpn Ags, and that CD8 ( + ) CTL to multiple epitopes inhibit Cpn growth in vitro
Zhang et al., J Virol 2005
(Eye Infections, Viral...) :
Th-cytotoxic T-lymphocyte chimeric epitopes extended by Nepsilon-palmitoyl lysines induce herpes simplex virus type 1-specific effector
CD8+ Tc1 responses and protect against ocular infection
Aizu et al., Eur J Immunol 2006
(Listeriosis) :
Using an adoptive transfer system of OT-I cells expressing OVA ( 257-264 ) /Kb-specific TCR into Tyk2-/- mice followed by challenge with recombinant L. monocytogenes expressing OVA, we found that the defective Tyk2 signaling in the host environment was at least partially responsible for the impaired
CD8+ T cytotoxic-1 (Tc1) cell
responses in Tyk2-/- mice following the infection
Dobrzanski et al., J Immunol 2006
(Breast Neoplasms) :
Tc1 mediated responses markedly
enhanced the appearance and local accumulation of highly differentiated ( CD44 ( high ) ) CD4 and
CD8 endogenous tumor infiltrating T cells when compared with that of untreated tumor bearing mice
Field et al., J Lab Clin Med 1998
:
Thus tolerance is associated with the inhibition of Th1 CD4 and
TC1 CD8 responses and the enhancement of Th2 CD4 responses