Kasai et al., Arterioscler Thromb Vasc Biol 2008
:
The reduced responses to VEGF and FGF2 in apelin-KO mice were partially restored by apelin, but apelin alone did not induce angiogenesis
Kim et al., Nat Med 2013
(Hypertension, Pulmonary...) :
APLN deficiency in these cells led to increased expression of FGF2 and its receptor FGFR1 as a consequence of decreased expression of miR-424 and miR-503, which directly target FGF2 and FGFR1