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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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IL8 — MMP21

Text-mined interactions from Literome

Meisser et al., Mol Hum Reprod 1999 : The aim of this study was to determine the effects of tumour necrosis factor alpha (TNF), interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
Watanabe et al., Oral Oncol 2002 (Carcinoma, Squamous Cell...) : Second, we thus also investigated the effect of IL-8 on MMP release in OSCC cells
Sun et al., Connect Tissue Res 2003 (Arthritis, Rheumatoid) : Furthermore, the induction of the MMP expression and activities by interleukin-1 was suppressed by the oscillatory shear
Mulayim et al., Fertil Steril 2004 : To evaluate the effect of interleukin-8 (IL-8) on endometrial stromal cell metalloproteinase ( MMP ) activity and invasiveness ... IL-8 increases MMP activity and invasive capability of endometrial stromal cells in culture ; IL-8 may be involved in the pathogenesis of endometriosis and menstrual physiology
So et al., Gynecol Oncol 2004 (Neoplasm Invasiveness...) : IL-8 did not affect cellular migration, MMP2 activation, or uPA expression
Hanrahan et al., J Clin Oncol 2010 (Lung Neoplasms) : For example, increases in IL-8 with VCP, MMP-9 with CP, and VEGF with vandetanib monotherapy were associated with increased progression risk, and increase in intercellular adhesion molecule 1 with vandetanib was associated with decreased risk
Thirkettle et al., J Biol Chem 2013 (Breast Neoplasms) : In particular, MMP-8 proteolytically activates IL-8 and, thereby, regulates neutrophil chemotaxis in vivo