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AGTR2 — PARP1

Text-mined interactions from Literome

Gendron et al., J Biol Chem 2003 : In the present report, we demonstrate that activation of the AT(2) receptor rapidly, but transiently, activated the Rap1/B-Raf complex of signaling proteins
Reinemund et al., Biochem Pharmacol 2009 : Poly(ADP-ribose) polymerase-1 ( PARP-1 ) transcriptionally regulates angiotensin AT2 receptor (AT2R) and AT2R binding protein (ATBP) genes ... Overexpression, pharmacological inhibition and ablation of PARP demonstrated that PARP-1 activates the ATIP1 gene but represses the AT2R on promoter and mRNA levels in vitro, and in brain tissue in vivo
Guimond et al., Mol Cell Neurosci 2010 : Thus, although SKF activity is required to achieve AT(2) induced activation of TrkA, Rap1 and p42/p44(mapk), Fyn is essential for AT(2) receptor induced neurite outgrowth, but not in AT(2) signaling leading to p42/p44(mapk) activation