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TRPC3 — VEGFA
Text-mined interactions from Literome
Poteser et al., FEBS Lett 2008
:
High levels of
VEGF induced Ca2+ entry and
TRPC3 expression were preferentially detected in rim areas of expanding colonies
Ge et al., Cancer Lett 2009
:
Transient receptor potential canonical (
TRPC ) channel 6, a Ca ( 2+ ) -permeable non-selective cation channel, can be
activated by
VEGF
Wang et al., Neurosci Lett 2009
:
These results suggest TRPC channels were involved in hypoxia induced
VEGF expression, and compared with other TRPC isoforms,
TRPC1 might
play a different role in this process ... However, overexpression of
TRPC3 or 5 neither
enhanced hypoxia induced
VEGF expression, nor prevented it ... Taken together, our present data suggest that TRPC1, but not
TRPC3 or 5, is
involved in hypoxia induced
VEGF expression in U-87 MG cells