Gene interactions and pathways from curated databases and text-mining

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TRPC3 — VEGFA

Text-mined interactions from Literome

Poteser et al., FEBS Lett 2008 : High levels of VEGF induced Ca2+ entry and TRPC3 expression were preferentially detected in rim areas of expanding colonies
Ge et al., Cancer Lett 2009 : Transient receptor potential canonical ( TRPC ) channel 6, a Ca ( 2+ ) -permeable non-selective cation channel, can be activated by VEGF
Wang et al., Neurosci Lett 2009 : These results suggest TRPC channels were involved in hypoxia induced VEGF expression, and compared with other TRPC isoforms, TRPC1 might play a different role in this process ... However, overexpression of TRPC3 or 5 neither enhanced hypoxia induced VEGF expression, nor prevented it ... Taken together, our present data suggest that TRPC1, but not TRPC3 or 5, is involved in hypoxia induced VEGF expression in U-87 MG cells