Gene interactions and pathways from curated databases and text-mining

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AKT1 — CSF3

Text-mined interactions from Literome

Dong et al., J Immunol 2001 (Leukemia, Myeloid, Acute...) : Our results indicate further that this regulation is highly specific because SHP-1 has no effect on the activation of Akt and extracellular signal related kinase1/2 by G-CSF
Zhuang et al., J Leukoc Biol 2005 : Using a series of tyrosine-to-phenylalanine substitution mutants, we show here that tyrosine (Tyr) 729, located in the carboxy terminus of the G-CSF-R, controls the duration of G-CSF stimulated activation of Stat5, Akt , and extracellular signal regulated kinase 1/2
Miyata et al., Am J Pathol 2006 (Cardiomyopathy, Dilated...) : Granulocyte colony stimulating factor also down-regulated tumor necrosis factor-alpha and increased activities of Akt signal transducer and activator of transcription-3, and matrix metalloproteinases
Liu et al., J Immunol 2006 : We show in this study that G-CSF induced activation of Akt in myeloid 32D was specifically inhibited by treatment with PMA, a protein kinase C ( PKC ) activator
Shih et al., PloS one 2012 : Furthermore, aciculatin significantly inhibited the G-CSF mediated phosphorylation of Janus kinase-signal transducer and activator of transcription ( JAK-STAT ) and Akt and neutrophil differentiation from precursor cells
Souza et al., J Leukoc Biol 2013 : G-CSF activation of AKT is not sufficient to prolong neutrophil survival ... Our results demonstrate that G-CSF activation of AKT is not sufficient to prolong neutrophil survival