Ho et al., Blood 2002
:
Our data reveal the requirement of ERK activation by TEL-JAK2 ( 5-19 ) in Ba/F3 cells and suggest that TEL-JAK2 leukemogenic potential may be mediated in part through ERK1/2
Wheadon et al., Blood 2003
:
We demonstrate that TEL/PDGFbetaR expression augmented IL-3 induced activation of PKB, STAT5, ERK1/2 , p38, and JNK1/2
Maki et al., Mol Cell Biol 2004
(MAP Kinase Signaling System) :
These data indicate that TEL is a constituent downstream of ERK in signal transduction systems and is physiologically regulated by ERK in molecular and biological features