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NFKB1 — PECAM1
Text-mined interactions from Literome
Botella et al., J Immunol 2000
:
Mobility shifts assays identified a specific NF-kappa B-binding element at +110/+120, whose mutation abolished the basal promoter activity of PECAM-1 and decreased
NF-kappa B-dependent responses of the
PECAM-1 gene promoter ... These results demonstrate that
NF-kappa B can
regulate the transcriptional activity of
PECAM-1
Rui et al., J Immunol 2007
:
In this study, we demonstrate that
PECAM-1 ligation with CD38-Fc fusion protein negatively
regulates LPS induced proinflammatory cytokine TNF-alpha, IL-6, and IFN-beta production by inhibiting JNK,
NF-kappaB , and IFN regulatory factor 3 activation in macrophages
Chen et al., Arterioscler Thromb Vasc Biol 2009
(Coronary Restenosis...) :
Inward remodeling was associated with
PECAM-1 dependent
NFkappaB activation, surface adhesion molecule expression, and leukocyte infiltration as well as Akt activation and vascular cell proliferation
Privratsky et al., J Immunol 2010
:
To confirm and extend these observations, we examined the
effect of engaging, cross linking, or expressing
PECAM-1 on
NF-kappaB activation in a variety of human cells