Hsu et al., J Diabetes Complications 2005
:
Under 30 mM glucose stress, GPx activity significantly decreased, and lactate dehydrogenase ( LDH ) release, H2O2 level, and Fn and VEGF production significantly increased in HUVECs ( P < .05 )
Rohr-Udilova et al., Hepatology 2012
(Carcinoma, Hepatocellular...) :
Selenium enhanced GPx4 expression and total GPx activity, while knock-down of GPx4 by small interfering RNA ( siRNA ) increased VEGF , and IL-8 expression