◀ Back to IL6

FLT3LG — IL6

Text-mined interactions from Literome

Peters et al., Exp Hematol 2001 : Moreover, on murine NIH/3T3 fibroblasts and on human primary forskin fibroblasts, stimulation with the IL-6/sIL-6R complex, and to a lesser extent with IL-6 alone, led to induction of cellular SCF and Flt-3L expression ... We showed that IL-6 in combination with its soluble receptor stimulates cellular SCF and Flt-3L expression in vivo and in vitro ... Cellular upregulation of SCF and Flt-3L by IL-6/sIL-6R might be used for the development of new stroma cell systems for ex vivo expansion of hematopoietic progenitor cells
McGee et al., Am J Respir Cell Mol Biol 2010 (Bronchial Hyperreactivity) : These data suggest that the therapeutic effect of Flt3-L in reversing the hallmarks of allergic asthma in a mouse model is mediated by decreasing IL-6 and TGF-ß levels in the BALF, which, in turn, decrease CD4 ( + ) IL-17 ( + ) IL-23R ( + ) ROR-?t ( + ) CD25? T cells and the expression of SOCS-1 and SOCS-3 in the lung of HDM sensitized and -challenged mice