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PXN — VEGFA

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: PXN → VEGFA (increases, VEGFA Activity)
  Evidence: VEGF increases tyrosine phosphorylation and focal adhesion association of FAK and paxillin
• OpenBEL Selventa BEL large corpus: PXN → VEGFA (increases)
  Evidence: VEGF increases tyrosine phosphorylation and focal adhesion association of FAK and paxillin
• Reactome Reaction: PXN → VEGFA (reaction) Schaller et al., Biochem J 2001, Abedi et al., J Biol Chem 1997
• Reactome Reaction: PXN → VEGFA (indirect_complex) Schaller et al., Biochem J 2001, Abedi et al., J Biol Chem 1997

Text-mined interactions from Literome

Dougher et al., Oncogene 1999 : VEGF binding to cells expressing the native receptor led to a rapid increase in receptor and PLC-gamma phosphorylation, and a slower increase in the phosphorylation of p125FAK and paxillin
Takahashi et al., Circ Res 1999 : VEGF induced tyrosine phosphorylation and activation of p125(FAK) as well as tyrosine phosphorylation of paxillin ; this was accompanied by subcellular translocation of p125(FAK) from perinuclear sites to the focal adhesions
Shin et al., Biochem Biophys Res Commun 2008 : sPTK7 reduced VEGF induced phosphorylation of focal adhesion kinase ( FAK ) and paxillin , relocalization of paxillin to focal adhesions, and formation of stress fibers
Liao et al., Endocrinology 2010 : c-Src inhibition suppressed VEGF induced phosphorylation of focal adhesion kinase, paxillin , and focal adhesion
Abedi et al., J Biol Chem 1997 : VEGF stimulated migration and actin stress fiber formation in confluent HUVEC, and VEGF induced p125(FAK)/paxillin tyrosine phosphorylation was accompanied by increased immunofluorescent staining of p125(FAK), paxillin, and phosphotyrosine in focal adhesions in confluent cultures of HUVECs