Gene interactions and pathways from curated databases and text-mining

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CDKN1A — KRAS

Text-mined interactions from Literome

Ramakrishna et al., Mol Carcinog 2000 (Adenoma...) : One hypothesis is that Ki-ras mutation and/or a Ki-ras p21 increase could enhance Ki-ras p21-GTP and cell-cycle stimulation through raf-1 and extracellularly regulated protein kinases ( Erks )
Itoh et al., Proc Natl Acad Sci U S A 1993 : Both factors were necessary for Ki-ras p21 dependent activation of MAP kinase/ERK2