◀ Back to GYS1

GSK3A — GYS1

Pathways - manually collected, often from reviews:

• WikiPathways Glycogen Metabolism: GSK3B/GSK3A → GYS1/GYS2 (inhibition)
• WikiPathways Angiopoietin Like Protein 8 Regulatory Pathway: GSK3A/GSK3B → GYS1 (inhibition)

Text-mined interactions from Literome

Højlund et al., Diabetologia 2006 : Insulin increased Akt phosphorylation at Ser473 and Thr308, inhibited glycogen synthase kinase-3alpha activity, reduced phosphorylation of glycogen synthase at sites 3a+3b, and increased glycogen synthase activity in Arg1174Gln carriers ( all p < 0.05 )
Fediuc et al., Endocrinology 2006 : Our results indicate that AICAR induced AMP activated protein kinase activation caused a time dependent reduction in Akt308 phosphorylation, activation of glycogen synthase kinase-3alpha/beta , and the inactivation of glycogen synthase , which are compatible with the acute reduction in insulin stimulated glycogen synthesis in oxidative but not glycolytic skeletal muscles