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NTRK2 — SLC22A3

Text-mined interactions from Literome

Smit et al., Mol Cell Biol 2009 (Neoplasm Metastasis) : This required TrkB kinase activity, a functional mitogen activated protein kinase pathway, suppression of E-cadherin, and induction of Twist, a transcription factor contributing to EMT and metastasis
Kupferman et al., Oncogene 2010 (Carcinoma, Squamous Cell...) : TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma
Smit et al., Oncogene 2011 (Neoplasm Metastasis) : We show here that Zeb1 is required for TrkB induced EMT in epithelial cells, as RNAi mediated knockdown of Zeb1 reverted the morphological changes induced by TrkB
Fujikawa et al., J Gastroenterol 2012 (Adenocarcinoma...) : This study investigates whether TrkB expression is associated with the clinical outcome of colorectal cancer ( CRC ) patients and whether TrkB induces EMT in CRC cells ... These results indicate TrkB could induce EMT and play an important role in CRC progression to metastasis