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GP5 — SYK

Text-mined interactions from Literome

Suzuki-Inoue et al., Biochem J 2004 : Glycoproteins GPVI and GPIb-IX-V stimulate robust tyrosine phosphorylation of Syk and PLCg2 ( phospholipase Cg2 ) in washed platelets, but only the former stimulates pronounced activation of phospholipase ... Using phospho-specific antibodies, we demonstrate that GPVI, but not GPIb-IX-V , stimulates significant tyrosine phosphorylation of Syk at the autophosphorylation site pY525/526, a marker of Syk activity
Ohta et al., Biochem Biophys Res Commun 1992 : These data suggest that p72syk is a candidate of responsible protein-tyrosine kinase for platelet activation and that cell surface glycoprotein is involved in the activation of p72syk in platelets