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ARSA — PTGS2

Text-mined interactions from Literome

Yao et al., Exp Lung Res 2000 (Adenoma...) : ASA ( 294 mg/kg diet ) and NS398 also inhibited the expression of COX-2
Williams et al., Cancer Res 2003 (Colonic Neoplasms) : Interestingly, NO-ASA induced COX-2 expression, although it had no effect on COX-1
Mortaz et al., Biochem Pharmacol 2005 : ASA blocked the expression of cyclooxygenase-2 , the production of tumor necrosis factor-alpha and interleukin-6, and the release of granule mediators from mast cells in a concentration dependent fashion ... Interestingly, the expression of cyclooxygenase-2 was not inhibited at 1mM ASA , but was even enhanced significantly
Konturek et al., J Physiol Pharmacol 2006 (Helicobacter Infections) : Both ASA and ASA-VitC stimulated the COX-2 expression in the gastric mucosa
Trujillo-Murillo et al., J Viral Hepat 2007 (Hepatitis C) : Our results suggest that COX-2 activity is involved in ethanol induced HCV-RNA and NS5A protein expression, because acetylsalicylic acid (ASA) , a COX-1/2 inhibitor , blocked this induction and downregulated COX-2 protein expression and activity
Zhou et al., Cancer Lett 2009 (Necrosis...) : NO-ASA induced COX-2 expression starting 90 min after p21 ( cip-1 ) was induced