Gene interactions and pathways from curated databases and text-mining

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PTGS2 — WNK1

Text-mined interactions from Literome

Ding et al., J Biol Chem 2006 : Moreover, the NF-kappaB p65 , and not the p50 subunit, was critical for nickel induced COX-2 expression
Cho et al., Mol Endocrinol 2009 : Chromatin immunoprecipitation and transfection assays revealed that a p65 DNA complex involving GR-bound GR-interacting protein 1 (GRIP1) also contributed to COX-2 repression
El-Bikai et al., Arthritis Res Ther 2010 (Osteoarthritis) : It inhibited a1ß1 integrin and Col II expression as well as ERK1/2 and NF-?B-p65 phosphorylation, but, in contrast, markedly elicited PGE2 release, COX-2 expression and p38 MAPK phosphorylation