Bruning et al., Proc Natl Acad Sci U S A 2000
:
Thus Rsk-2 is required for growth factor stimulated expression of c-Fos and transcriptional activation of Elk-1 and the serum response factor, but not for activation of CREB or the mitogen activated protein kinase pathway in response to PDGF and IGF-1 stimulation
Huttunen et al., J Biol Chem 2002
(Neuroblastoma) :
Furthermore, inhibition of ERK1/2-Rsk2 dependent CREB phosphorylation efficiently inhibited up-regulation of chromogranin gene expression upon RAGE activation
Vaidyanathan et al., J Biol Chem 2003
:
We show that this interaction has functional consequences including the inhibition of RSK2 dependent CREB transcription
De Cesare et al., Proc Natl Acad Sci U S A 1998
:
Rsk-2 activity is necessary for epidermal growth factor induced phosphorylation of CREB protein and transcription of c-fos gene
Impey et al., Neuron 1998
(Calcium Signaling) :
The sequential activation of ERK and Rsk2 by Ca2+ leads to the phosphorylation and transactivation of CREB