Gene interactions and pathways from curated databases and text-mining

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DRD1 — EPHB2

Text-mined interactions from Literome

Chan et al., J Neurochem 2005 (Brain Neoplasms...) : Stimulation of the Gi-coupled neuropeptide Y1 and Gq-coupled muscarinic M1 acetylcholine receptors, but not the Gs-coupled dopamine D1 receptor , led to the activation of extracellular signal regulated kinase ( ERK )
Borgkvist et al., Neuropharmacology 2008 (Morphine Dependence) : Delayed, context- and dopamine D1 receptor dependent activation of ERK in morphine sensitized mice
Gerfen et al., J Neurosci 2008 : In the normal dorsal striatum, there is minimal Drd1a mediated activation of ERK1/2 ; however, in the PD model there is robust Drd1a mediated activation of ERK1/2
Xu et al., Life Sci 2013 (MAP Kinase Signaling System) : PKA and ERK1/2 are involved in dopamine D1 receptor induced heterologous desensitization of the d opioid receptor