◀ Back to AR

AR — PAK6

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: AR → Complex of AR-PAK6 (directlyDecreases, AR/PAK6 Activity)
  Evidence: PAK6 was first identified as an androgen receptor (AR)-interacting protein able to inhibit AR-mediated transcriptional responses. We show that PAK6 kinase activity is required for effective PAK6-induced repression of AR signaling.
• OpenBEL Selventa BEL large corpus: AR → PAK6 (directlyDecreases, PAK6 Activity, AR Activity)
  Evidence: PAK6 was first identified as an androgen receptor (AR)-interacting protein able to inhibit AR-mediated transcriptional responses. We show that PAK6 kinase activity is required for effective PAK6-induced repression of AR signaling.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: AR — PAK6 (direct interaction, enzymatic study) Liu et al., J Biol Chem 2013*
• IRef Biogrid Interaction: AR — PAK6 (direct interaction, pull down) Lee et al., Mol Endocrinol 2002*
• IRef Biogrid Interaction: AR — PAK6 (direct interaction, two hybrid) Lee et al., Mol Endocrinol 2002*
• IRef Biogrid Interaction: AR — PAK6 (physical association, affinity chromatography technology) Yang et al., J Biol Chem 2001*
• IRef Biogrid Interaction: AR — PAK6 (direct interaction, pull down) Yang et al., J Biol Chem 2001*
• IRef Biogrid Interaction: AR — PAK6 (direct interaction, two hybrid) Yang et al., J Biol Chem 2001*
• IRef Hprd Interaction: AR — PAK6 (two hybrid) Yang et al., J Biol Chem 2001*
• IRef Hprd Interaction: AR — PAK6 (in vivo) Yang et al., J Biol Chem 2001*
• IRef Hprd Interaction: AR — PAK6 (in vitro) Yang et al., J Biol Chem 2001*
• IRef Ophid Interaction: AR — PAK6 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005