Skjolaas et al., Vet Immunol Immunopathol 2002
:
Both 150 and 300 nM CORT suppressed IL-10 at 24 h ( P < 0.05 ), but neither concentration affected IFNgamma at 24 h ... At both 12 and 24 h, IL-10 was reduced by 300 nM DEX and by 150 and 300 nM CORT ( P < 0.05 )
Gonzalez-Rey et al., Ann Rheum Dis 2007
(Arthritis, Experimental...) :
Cortistatin downregulated the production of various inflammatory cytokines and chemokines, decreased the antigen-specific Th1-cell expansion, and induced the production of regulatory cytokines, such as interleukin 10 and transforming growth factor beta1