Gene interactions and pathways from curated databases and text-mining

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FCER2 — IL10

Text-mined interactions from Literome

Roever et al., Clin Exp Allergy 2003 (Conjunctivitis, Allergic...) : Allergen mediated modulation of CD23 expression is interferon-gamma and interleukin-10 dependent in allergic and non-allergic individuals
Bourget et al., Eur J Immunol 1995 : We show that B1 reduced both anti-mu + interleukin-4 (IL-4) induced DNA synthesis and the concomitant expression of CD23 at the surface of human tonsillar B cells
Spittler et al., Immunology 1995 : IL-10 augments CD23 expression on U937 cells and down-regulates IL-4-driven CD23 expression on cultured human blood monocytes : effects of IL-10 and other cytokines on cell phenotype and phagocytosis
Gagro et al., Eur J Immunol 1994 (Asthma) : In this study we investigated the effect of the Dermatophagoides pteronyssinus (Dpt) allergen and recombinant interleukin ( rIL ) -4 on the expression of CD21 and CD23 on T and B cells of asthmatic patients allergic to Dpt and of healthy controls
Dugas et al., Eur J Immunol 1996 : An anti-CD23 monoclonal antibody ( mAb ) was found to elicit the expression of the specific mRNA for IL-10 in CD23 bearing macrophages, and to induce a time dependent production of this cytokine with a maximal effect reached after 12 h. Inasmuch as we previously reported that CD23 ligation evoked the generation of nitric oxide and of cAMP, the effect of the Rp diastereoisomer of adenosine 3 ', 5'-cyclic phosphorothioate ( Rp-cAMP, an inhibitor of the cAMP pathway ) and of NG-monomethyl-L-arginine ( L-NMMA, an inhibitor of the nitric oxide pathway ) were evaluated on CD23 induced IL-10 production ... In the presence of Rp-cAMP, the CD23 induced production of IL-10 and of the pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) was totally abrogated, whereas, in the presence of L-NMMA, IL-10 production was enhanced and TNF-alpha production was suppressed
Ruzek et al., J Immunol 1996 (Plasmacytoma) : Collectively, these results demonstrate that plasma cell tumors down-regulate CD23 expression on B cells by a coordinate mechanism of IL-10 plus contact mediated events and reveal a novel role for IL-10 in the regulation of CD23 expression on B cells that is suggestive of host B cell activation in the presence of the tumor
Bécherel et al., J Immunol 1997 : Moreover, CD23 ligation induces IL-10 production in human monocytes ... Here, our data show that CD23 ligation induces significant IL-10 synthesis in HK, a phenomenon inhibited by cAMP antagonists, but not by inhibitors of the nitric oxide pathway ... These data indicate that engagement of surface CD23 on human keratinocytes induces the synthesis of IL-10 , which, in turn, down-regulates their proinflammatory response