Flott et al., Biochem J 2005
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Slx4 becomes phosphorylated after DNA damage in a Mec1/Tel1 dependent manner and is required for repair of DNA alkylation damage
Toh et al., DNA repair 2010
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Mec1/Tel1 dependent phosphorylation of Slx4 stimulates Rad1-Rad10 dependent cleavage of non-homologous DNA tails
Downey et al., Mol Cell 2010
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In this issue of Molecular Cell, Ohouo et al. ( 2010 ) show that Mec1 ( hATR ) promotes the association of Slx4 and Rtt107 with Dpb11 ( hTopBP1 ) in response to MMS induced DNA alkylation, suggesting that Slx4 and Rtt107 might coordinate repair factors specifically at damaged replication forks