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SRP14 — SRP9

Pathways - manually collected, often from reviews:

• Reactome Reaction: SRP9 → SRP14 (direct_complex)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: SRP14 — SRP9 Weichenrieder et al., Nature 2000*
• IRef Bind_translation Interaction: SRP14 — SRP9 (x-ray crystallography) Weichenrieder et al., Nature 2000*
• IRef Biogrid Interaction: SRP14 — SRP9 (direct interaction, pull down) Strub et al., Mol Cell Biol 1990*
• IRef Biogrid Interaction: SRP14 — SRP9 (colocalization, biochemical) Havugimana et al., Cell 2012
• IRef Biogrid Interaction: SRP14 — SRP9 (physical association, affinity chromatography technology) Piazzon et al., Nucleic Acids Res 2013
• IRef Biogrid Interaction: SRP14 — SRP9 (physical association, affinity chromatography technology) Kristensen et al., Nat Methods 2012
• IRef Biogrid Interaction: SRP14 — SRP9 (association, x-ray crystallography) Weichenrieder et al., Nature 2000*
• IRef Dip Interaction: SRP14 — SRP9 (direct interaction, x-ray crystallography) Weichenrieder et al., Nature 2000*
• IRef Hprd Interaction: SRP14 — SRP9 (in vitro) Weichenrieder et al., Nature 2000*, Strub et al., Mol Cell Biol 1990*
• IRef Intact Interaction: Complex of 228 proteins (association, pull down) Blagoev et al., Nat Biotechnol 2003
• IRef Intact Interaction: Complex of FBXW11-RAE1-SRP14-ACACA-SRP9-WDFY3-BTRC-EEF2K (association, tandem affinity purification) Varjosalo et al., Nat Methods 2013
• IRef Ophid Interaction: SRP14 — SRP9 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Mary et al., RNA 2010 : In eukaryotes, SRP has to arrest the elongation of the nascent chains during targeting to ensure efficient translocation of the preprotein, and this function of SRP is dependent on SRP9/14
Brown et al., EMBO J 1994 : Thus Srp14p , Srp21p, Srp68p and Srp72p, but not Sec65p or Srp54p, are required for stable expression of the yeast SRP