Gene interactions and pathways from curated databases and text-mining

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CDH1 — FHL2

Text-mined interactions from Literome

Wang et al., Gastroenterology 2007 (Cell Transformation, Neoplastic...) : FHL2 antisense induced expressions of carcinoembryonic antigen and E-cadherin and the maturation of F-actin
Zhang et al., Eur J Cancer 2011 (Colonic Neoplasms) : Four and a half LIM protein 2 (FHL2) negatively regulates the transcription of E-cadherin through interaction with Snail1 ... We previously demonstrated that four and a half LIM protein 2 (FHL2) inhibited E-cadherin expression and promoted invasive potential and EMT in colon cancer ... These results suggested that FHL2 negatively regulated E-cadherin transcriptional activity through interaction with Snail1