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A2M — MAPK6
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Misra et al., J Biol Chem 2002
:
Binding of
alpha(2)M* to macrophages, moreover,
increased phosphorylation of MEK 1/2, ERK 1/2, p38
MAPK , and JNK
Bonacci et al., Arch Biochem Biophys 2007
:
Activated
alpha(2)-macroglobulin induces cell proliferation and
mitogen activated protein kinase activation by LRP-1 in the J774 macrophage derived cell line ... In this work, we demonstrate that
alpha(2)M* binding to LRP-1
induces cell proliferation and
MAPK activation in the J774 macrophage derived cell line, which were blocked by RAP, an antagonist of LRP-1 binding ligands, and by PD980059, a specific inhibitor for the Mek1-ERK1/2 pathway