Gene interactions and pathways from curated databases and text-mining

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CA2 — GRK7

Text-mined interactions from Literome

Diverse-Pierluissi et al., Neuron 1996 (Synaptic Transmission) : G protein coupled receptor kinase mediates desensitization of norepinephrine induced Ca2+ channel inhibition
Haga et al., Biochemistry 1997 : These results indicate that Ca2+-calmodulin does not directly interact with the catalytic site of GRK2 but inhibits the kinase activity of GRK2 by interfering with the activation of GRK2 by agonist bound m2 receptors and G protein betagamma subunits ... In agreement with the assumption that GRK2 activity is suppressed by the increase in intracellular Ca2+ , the sequestration of m2 receptors expressed in Chinese hamster ovary cells was found to be attenuated by the treatment with a Ca2+ ionophore, A23187